6FHQ
Crystal structure of human BAZ2B PHD zinc finger in complex with Fr 21
Summary for 6FHQ
Entry DOI | 10.2210/pdb6fhq/pdb |
Descriptor | Bromodomain adjacent to zinc finger domain protein 2B, ZINC ION, 2-azanyl-~{N}-(1,3-thiazol-2-yl)ethanamide, ... (4 entities in total) |
Functional Keywords | transcription, phd, zinc finger, baz2b, baz2a, bromodomain, fragment, competition, epigenetic |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9UIF8 |
Total number of polymer chains | 2 |
Total formula weight | 13506.25 |
Authors | Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (deposition date: 2018-01-15, release date: 2018-03-21, Last modification date: 2024-01-17) |
Primary citation | Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach. ACS Chem. Biol., 13:915-921, 2018 Cited by PubMed: 29529862DOI: 10.1021/acschembio.7b01093 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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