6FFD
Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone
Summary for 6FFD
Entry DOI | 10.2210/pdb6ffd/pdb |
Descriptor | Bromodomain-containing protein 4, 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone (3 entities in total) |
Functional Keywords | inhibitor, histone, epigenetic reader, bromodomain, brd4, bromodomain containing protein 4, antagonist, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 13917.08 |
Authors | Chung, C. (deposition date: 2018-01-06, release date: 2019-01-30, Last modification date: 2024-05-08) |
Primary citation | Chung, C. Design and Synthesis of Tetrahydroquinoxalines as Domain Selective BET Inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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