6EVL
Crystal structure of an unlignaded peptide-substrate-binding domain of human type II collagen prolyl 4-hydroxylase
Summary for 6EVL
Entry DOI | 10.2210/pdb6evl/pdb |
Descriptor | Prolyl 4-hydroxylase subunit alpha-2, SULFATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | tetratricopeptide repeat, collagen synthesis, prolyl 4-hydroxylase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 12244.60 |
Authors | Murthy, A.V.,Sulu, R.,Koski, M.K.,Wierenga, R.K. (deposition date: 2017-11-02, release date: 2018-09-12, Last modification date: 2024-01-17) |
Primary citation | Murthy, A.V.,Sulu, R.,Koski, M.K.,Tu, H.,Anantharajan, J.,Sah-Teli, S.K.,Myllyharju, J.,Wierenga, R.K. Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif. Protein Sci., 27:1692-1703, 2018 Cited by PubMed: 30168208DOI: 10.1002/pro.3450 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
Download full validation report