6EPR
The ATAD2 bromodomain in complex with compound UZH-DS15
Summary for 6EPR
Entry DOI | 10.2210/pdb6epr/pdb |
Descriptor | ATPase family AAA domain-containing protein 2, (~{N}~{Z},2~{R})-~{N}-[5-(5-azanylpyridin-3-yl)-4-ethanoyl-3~{H}-1,3-thiazol-2-ylidene]-1-[2-[4,4-bis(fluoranyl)cyclohexyl]ethyl]piperazine-2-carboxamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | bromodomain, atad2, inhibitor, complex, cytosolic protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16042.16 |
Authors | Sledz, P.,Caflisch, A. (deposition date: 2017-10-12, release date: 2018-10-31, Last modification date: 2024-05-08) |
Primary citation | Sledz, P. Hitting a moving target: simulation and crystallography study of ATAD2 bromodomain blockers To Be Published, |
Experimental method |
Structure validation
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