6EJG

CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH SINGLE CHAIN FV FRAGMENT 4

Summary for 6EJG

Entry DOI	10.2210/pdb6ejg/pdb
Related	5DFW
Descriptor	CD81 antigen, SINGLE CHAIN FV FRAGMENT (3 entities in total)
Functional Keywords	helical bundle, antibody-antigen complex, cell adhesion
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	74642.96
Authors	Harris, S.F.,Wong, A.,Kuglstatter, A. (deposition date: 2017-09-21, release date: 2018-05-30, Last modification date: 2018-06-20)
Primary citation	Nelson, B.,Adams, J.,Kuglstatter, A.,Li, Z.,Harris, S.F.,Liu, Y.,Bohini, S.,Ma, H.,Klumpp, K.,Gao, J.,Sidhu, S.S. Structure-Guided Combinatorial Engineering Facilitates Affinity and Specificity Optimization of Anti-CD81 Antibodies. J. Mol. Biol., 430:2139-2152, 2018 Cited by PubMed: 29778602 DOI: 10.1016/j.jmb.2018.05.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.82 Å)

Structure validation