6D1W
human PKD2 F604P mutant
Summary for 6D1W
Entry DOI | 10.2210/pdb6d1w/pdb |
EMDB information | 7786 |
Descriptor | Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | ion channel, trp channel, pkd2, pc2, trpp2, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 342639.84 |
Authors | Zheng, W.,Yang, X.,Bulkley, D.,Chen, X.Z.,Cao, E. (deposition date: 2018-04-12, release date: 2018-06-27, Last modification date: 2020-07-29) |
Primary citation | Zheng, W.,Yang, X.,Hu, R.,Cai, R.,Hofmann, L.,Wang, Z.,Hu, Q.,Liu, X.,Bulkey, D.,Yu, Y.,Tang, J.,Flockerzi, V.,Cao, Y.,Cao, E.,Chen, X.Z. Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun, 9:2302-2302, 2018 Cited by PubMed: 29899465DOI: 10.1038/s41467-018-04586-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.54 Å) |
Structure validation
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