6CX0
Structure of AtTPC1 D376A
Summary for 6CX0
Entry DOI | 10.2210/pdb6cx0/pdb |
Descriptor | Two pore calcium channel protein 1, CALCIUM ION, (1S,3R)-1-(3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid (3 entities in total) |
Functional Keywords | ion channel, two-pore channel, tpc1, resting-state, closed, inactive, membrane protein, membrane protein-inhibitor complex, membrane protein/inhibitor |
Biological source | Arabidopsis thaliana (Mouse-ear cress) |
Total number of polymer chains | 1 |
Total formula weight | 85025.21 |
Authors | Kintzer, A.F.,Stroud, R.M. (deposition date: 2018-04-02, release date: 2018-09-19, Last modification date: 2023-10-04) |
Primary citation | Kintzer, A.F.,Green, E.M.,Dominik, P.K.,Bridges, M.,Armache, J.P.,Deneka, D.,Kim, S.S.,Hubbell, W.,Kossiakoff, A.A.,Cheng, Y.,Stroud, R.M. Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115:E9095-E9104, 2018 Cited by PubMed: 30190435DOI: 10.1073/pnas.1805651115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.501 Å) |
Structure validation
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