6CUZ
Engineered TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3R)-ethylserine bound as the amino-acrylate
Summary for 6CUZ
Entry DOI | 10.2210/pdb6cuz/pdb |
Descriptor | Tryptophan synthase beta chain 1, SODIUM ION, (2E)-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]pent-2-enoic acid, ... (6 entities in total) |
Functional Keywords | amino-acrylate, (2s, 3r)-ethylserine, lyase |
Biological source | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) More |
Total number of polymer chains | 4 |
Total formula weight | 170823.45 |
Authors | Scheele, R.A.,Buller, A.R.,Boville, C.E.,Arnold, F.H. (deposition date: 2018-03-27, release date: 2018-09-26, Last modification date: 2023-11-15) |
Primary citation | Boville, C.E.,Scheele, R.A.,Koch, P.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H. Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angew. Chem. Int. Ed. Engl., 57:14764-14768, 2018 Cited by PubMed: 30215880DOI: 10.1002/anie.201807998 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report