6CGC
Crystal structure of human 17beta-HSD type 1 in ternary complex with 2-MeO-CC-156 and NADP+
Summary for 6CGC
Entry DOI | 10.2210/pdb6cgc/pdb |
Descriptor | Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxy-2-methoxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, hydroxysteroid dehydrogenase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 72335.92 |
Authors | |
Primary citation | Li, T.,Maltais, R.,Poirier, D.,Lin, S.X. Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide. J Phys Chem Lett, 9:5275-5280, 2018 Cited by PubMed: 30148957DOI: 10.1021/acs.jpclett.8b02225 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report