6CEH
Design, Synthesis, X-ray and Biological Activities of Selenides Bearing the Benzenesulfonamide Moiety as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology
Summary for 6CEH
Entry DOI | 10.2210/pdb6ceh/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, 4-[(prop-2-en-1-yl)selanyl]benzene-1-sulfonamide, ... (6 entities in total) |
Functional Keywords | carbonic anhydrase inhibitors, diabetic pathology, organoselenium, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30059.92 |
Authors | Peat, T.S.,Angeli, A.,di Cesare Mannelli, L.,Trallori, E.,Ghelardini, C.,Carta, F.,Supuran, C.T. (deposition date: 2018-02-11, release date: 2018-05-23, Last modification date: 2023-10-04) |
Primary citation | Angeli, A.,di Cesare Mannelli, L.,Trallori, E.,Peat, T.S.,Ghelardini, C.,Carta, F.,Supuran, C.T. Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology. ACS Med Chem Lett, 9:462-467, 2018 Cited by PubMed: 29795760DOI: 10.1021/acsmedchemlett.8b00076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.43 Å) |
Structure validation
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