6C6Z
Crystal structure of potent neutralizing antibody CDC2-C2 in complex with MERS-CoV S1 RBD
Summary for 6C6Z
Entry DOI | 10.2210/pdb6c6z/pdb |
Descriptor | Spike protein, Antibody CDC2-C2 heavy chain, Antibody CDC2-C2 light chain, ... (5 entities in total) |
Functional Keywords | immune system, antibody, fusion glycoprotein, virus, antiviral protein |
Biological source | Middle East respiratory syndrome-related coronavirus More |
Total number of polymer chains | 6 |
Total formula weight | 149085.94 |
Authors | Wang, N.,McLellan, J.S. (deposition date: 2018-01-19, release date: 2018-01-31, Last modification date: 2023-10-04) |
Primary citation | Wang, L.,Shi, W.,Chappell, J.D.,Joyce, M.G.,Zhang, Y.,Kanekiyo, M.,Becker, M.M.,van Doremalen, N.,Fischer, R.,Wang, N.,Corbett, K.S.,Choe, M.,Mason, R.D.,Van Galen, J.G.,Zhou, T.,Saunders, K.O.,Tatti, K.M.,Haynes, L.M.,Kwong, P.D.,Modjarrad, K.,Kong, W.P.,McLellan, J.S.,Denison, M.R.,Munster, V.J.,Mascola, J.R.,Graham, B.S. Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J. Virol., 92:-, 2018 Cited by PubMed: 29514901DOI: 10.1128/JVI.02002-17 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report