6C6Z
Crystal structure of potent neutralizing antibody CDC2-C2 in complex with MERS-CoV S1 RBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Spike protein | polymer | 231 | 25337.5 | 2 | UniProt (A0A0U2MS80) Pfam (PF09408) UniProt (by SIFTS) (K9N5Q8) | Middle East respiratory syndrome-related coronavirus | |
| 2 | C, E (C, H) | Antibody CDC2-C2 heavy chain | polymer | 239 | 25171.2 | 2 | Homo sapiens (Human) | ||
| 3 | D, F (D, L) | Antibody CDC2-C2 light chain | polymer | 218 | 23702.4 | 2 | Homo sapiens (Human) | ||
| 4 | G, H, I (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | J, K, L, M, N... (A, B, C, D, H...) | water | water | 18.0 | 719 | Chemie (HOH) |
Sequence modifications
A, B: 367 - 589 (UniProt: A0A0U2MS80)
| PDB | External Database | Details |
|---|---|---|
| Phe 506 | Leu 506 | conflict |
| Gly 590 | - | expression tag |
| Ser 591 | - | expression tag |
| Leu 592 | - | expression tag |
| Glu 593 | - | expression tag |
| Val 594 | - | expression tag |
| Leu 595 | - | expression tag |
| Phe 596 | - | expression tag |
| Gln 597 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 148422.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 149085.9 |
