6C5H
S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen
Summary for 6C5H
Entry DOI | 10.2210/pdb6c5h/pdb |
Descriptor | Fab Heavy Chain (IgG1), Fab Light Chain (IgG1 Kappa), alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | complex, lipopolysaccharide, antibody, antigen, chlamydia, sugar binding protein, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 49806.53 |
Authors | Evans, S.V.,Haji-Ghassemi, O. (deposition date: 2018-01-16, release date: 2019-01-09, Last modification date: 2023-10-04) |
Primary citation | Haji-Ghassemi, O.,Muller-Loennies, S.,Brooks, C.L.,MacKenzie, C.R.,Caveney, N.,Van Petegem, F.,Brade, L.,Kosma, P.,Brade, H.,Evans, S.V. Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry, 58:714-726, 2019 Cited by PubMed: 30571096DOI: 10.1021/acs.biochem.8b00318 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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