6BSZ
Human mGlu8 Receptor complexed with glutamate
Summary for 6BSZ
Entry DOI | 10.2210/pdb6bsz/pdb |
Descriptor | Metabotropic glutamate receptor 8, GLUTAMIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | mglur8, grm8, glutamate, gene id: 2918, signaling protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Multi-pass membrane protein: O00222 |
Total number of polymer chains | 2 |
Total formula weight | 108159.83 |
Authors | Schkeryantz, J.M.,Chen, Q.,Ho, J.D.,Atwell, S.,Zhang, A.,Vargas, M.C.,Wang, J.,Monn, J.A.,Hao, J. (deposition date: 2017-12-04, release date: 2018-02-07, Last modification date: 2023-10-25) |
Primary citation | Schkeryantz, J.M.,Chen, Q.,Ho, J.D.,Atwell, S.,Zhang, A.,Vargas, M.C.,Wang, J.,Monn, J.A.,Hao, J. Determination of L-AP4-bound human mGlu8 receptor amino terminal domain structure and the molecular basis for L-AP4's group III mGlu receptor functional potency and selectivity. Bioorg. Med. Chem. Lett., 28:612-617, 2018 Cited by PubMed: 29402739DOI: 10.1016/j.bmcl.2018.01.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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