6BQV
Human TRPM4 ion channel in lipid nanodiscs in a calcium-bound state
Summary for 6BQV
Entry DOI | 10.2210/pdb6bqv/pdb |
EMDB information | 7132 7133 |
Descriptor | Transient receptor potential cation channel subfamily M member 4, CALCIUM ION, CHOLESTEROL HEMISUCCINATE (3 entities in total) |
Functional Keywords | trpm4, trpm channel, trp channel, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 545083.96 |
Authors | Autzen, H.E.,Myasnikov, A.G.,Campbell, M.G.,Asarnow, D.,Julius, D.,Cheng, Y. (deposition date: 2017-11-28, release date: 2017-12-20, Last modification date: 2024-03-13) |
Primary citation | Autzen, H.E.,Myasnikov, A.G.,Campbell, M.G.,Asarnow, D.,Julius, D.,Cheng, Y. Structure of the human TRPM4 ion channel in a lipid nanodisc. Science, 359:228-232, 2018 Cited by PubMed: 29217581DOI: 10.1126/science.aar4510 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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