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6BQV

Human TRPM4 ion channel in lipid nanodiscs in a calcium-bound state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily M member 4polymer1218134770.74UniProt (Q8TD43)
Pfam (PF18139)
Pfam (PF00520)
Homo sapiens (Human)hTRPM4, Calcium-activated non-selective cation channel 1, Long transient receptor potential channel 4, LTrpC4, Melastatin-4
2E, I, M, Q
(A, B, C, D)
CALCIUM IONnon-polymer40.14Chemie (CA)
3F, G, H, J, K...
(A, B, C, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.712Chemie (Y01)
Sequence modifications
A, B, C, D: 2 - 1214 (UniProt: Q8TD43)
PDBExternal DatabaseDetails
Ser -3-expression tag
Gly -2-expression tag
Arg -1-expression tag
Ser 0-expression tag
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight539082.9
Non-Polymers*Number of molecules16
Total formula weight6001.0
All*Total formula weight545084.0
*Water molecules are not included.

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PDB entries from 2025-06-25

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