6BQV
Human TRPM4 ion channel in lipid nanodiscs in a calcium-bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily M member 4 | polymer | 1218 | 134770.7 | 4 | UniProt (Q8TD43) Pfam (PF18139) Pfam (PF25508) Pfam (PF00520) | Homo sapiens (Human) | hTRPM4, Calcium-activated non-selective cation channel 1, Long transient receptor potential channel 4, LTrpC4, Melastatin-4 |
| 2 | E, I, M, Q (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) PubChem (271) | |||
| 3 | F, G, H, J, K... (A, B, C, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) PubChem (65082) PubChem (363416) PubChem (500055) PubChem (13301926) PubChem (13301927) PubChem (16219150) PubChem (22210610) PubChem (45489984) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A, B, C, D: 2 - 1214 (UniProt: Q8TD43)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Arg -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 539082.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 6001.0 | |
| All* | Total formula weight | 545084.0 |
