6BPC

Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 4F7

Summary for 6BPC

• Entry DOI: 10.2210/pdb6bpc/pdb
• Related: 6BPA 6BPB 6BPD 6BPE
• Descriptor: Reticulocyte binding protein 2, putative, Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain, ... (4 entities in total)
• Functional Keywords: plasmodium vivax, invasion, malaria, antibody complex, cell invasion
• Biological source: Plasmodium vivax (strain Salvador I); More
• Total number of polymer chains: 6
• Total formula weight: 180534.18

Authors

Gruszczyk, J.,Chan, L.J.,Tham, W.H. (deposition date: 2017-11-22, release date: 2018-06-20, Last modification date: 2023-10-04)

• Primary citation: Gruszczyk, J.,Huang, R.K.,Chan, L.J.,Menant, S.,Hong, C.,Murphy, J.M.,Mok, Y.F.,Griffin, M.D.W.,Pearson, R.D.,Wong, W.,Cowman, A.F.,Yu, Z.,Tham, W.H.; Cryo-EM structure of an essential Plasmodium vivax invasion complex.; Nature, 559:135-139, 2018; PubMed: 29950717; DOI: 10.1038/s41586-018-0249-1

Experimental method

X-RAY DIFFRACTION (2.66 Å)