6BGT

Structure of Trastuzumab Fab mutant in complex with Her2 extracellular domain

Summary for 6BGT

• Entry DOI: 10.2210/pdb6bgt/pdb
• Related: 6ARP 6ARU 6BFT
• Descriptor: Receptor tyrosine-protein kinase erbB-2, Herceptin light chain mutant, Herceptin heavy chain Fab fragment mutant, ... (5 entities in total)
• Functional Keywords: herceptin, antibody, transferase-immune system complex, transferase/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 120918.22

Authors

Christie, M.,Christ, D. (deposition date: 2017-10-29, release date: 2018-10-31, Last modification date: 2023-10-04)

• Primary citation: Christie, M.,Rouet, R.,Nevoltris, D.,Langley, D.,Schofield, P.,Fabri, L.,Tingly, K.,Lowe, D.,Jermutus, L.,Christ, D.; Stable human IgG antibody therapeutics with native framework structure; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)