6AAC

Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys

Summary for 6AAC

Entry DOI	10.2210/pdb6aac/pdb
Descriptor	Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (8 entities in total)
Functional Keywords	aminoacyl-trna synthetase, non-natural amino acids, translation
Biological source	Methanosarcina mazei JCM 9314 (Methanosarcina frisia)
Total number of polymer chains	1
Total formula weight	32543.80
Authors	Yanagisawa, T.,Kuratani, M.,Yokoyama, S. (deposition date: 2018-07-18, release date: 2019-04-17, Last modification date: 2023-11-22)
Primary citation	Yanagisawa, T.,Kuratani, M.,Seki, E.,Hino, N.,Sakamoto, K.,Yokoyama, S. Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26:936-, 2019 Cited by PubMed: 31031143 DOI: 10.1016/j.chembiol.2019.03.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.479 Å)

Structure validation