6AAC

Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 501

Chain	Residue
A	ATP504
A	HOH654
A	HOH664
A	HOH723
A	HOH733

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 502

Chain	Residue
A	HOH643
A	HOH750
A	GLU396
A	SER399
A	MG503
A	ATP504

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 503

Chain	Residue
A	GLU396
A	MG502
A	ATP504
A	HOH643
A	HOH804
A	HOH813

---

site_id	AC4
Number of Residues	29
Details	binding site for residue ATP A 504

Chain	Residue
A	ARG330
A	GLU332
A	HIS338
A	LEU339
A	PHE342
A	MET344
A	GLU396
A	LEU397
A	SER398
A	SER399
A	GLY421
A	GLY423
A	ARG426
A	MG501
A	MG502
A	MG503
A	9TR505
A	HOH643
A	HOH654
A	HOH664
A	HOH666
A	HOH723
A	HOH728
A	HOH733
A	HOH750
A	HOH767
A	HOH772
A	HOH800
A	HOH804

---

site_id	AC5
Number of Residues	13
Details	binding site for residue 9TR A 505

Chain	Residue
A	MET276
A	ALA302
A	ALA306
A	LEU309
A	ASN346
A	PHE384
A	SER399
A	LEU407
A	ASP408
A	ILE413
A	TRP417
A	ATP504
A	HOH802

---

site_id	AC6
Number of Residues	6
Details	binding site for residue K A 506

Chain	Residue
A	ASN203
A	PRO204
A	ASP206
A	HOH610
A	HOH798
A	HOH865

---

site_id	AC7
Number of Residues	8
Details	binding site for residue PEG A 507

Chain	Residue
A	SER333
A	ASP334
A	GLY335
A	LYS336
A	GLU337
A	HIS338
A	PGE508
A	HOH663

---

site_id	AC8
Number of Residues	7
Details	binding site for residue PGE A 508

Chain	Residue
A	LEU370
A	GLY371
A	VAL430
A	LYS431
A	ASP433
A	PEG507
A	HOH628

---