6A3W
Complex structure of 4-1BB and utomilumab
Summary for 6A3W
Entry DOI | 10.2210/pdb6a3w/pdb |
Descriptor | utomilumab VH, utomilumab VL, Tumor necrosis factor receptor superfamily member 9, ... (5 entities in total) |
Functional Keywords | complex structure, 4-1bb, angonist monoclonal antibody, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 167968.02 |
Authors | |
Primary citation | Li, Y.,Tan, S.,Zhang, C.,Chai, Y.,He, M.,Zhang, C.W.,Wang, Q.,Tong, Z.,Liu, K.,Lei, Y.,Liu, W.J.,Liu, Y.,Tian, Z.,Cao, X.,Yan, J.,Qi, J.,Tien, P.,Gao, S.,Gao, G.F. Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep, 25:909-920.e4, 2018 Cited by PubMed: 30355497DOI: 10.1016/j.celrep.2018.09.073 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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