6A3W

Complex structure of 4-1BB and utomilumab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	utomilumab VH	polymer	116	12869.4	4		Homo sapiens (Human)
2	B, E, H, K (B, E, H, K)	utomilumab VL	polymer	109	11543.6	4		Homo sapiens (Human)
3	C, F, I, L (C, F, I, L)	Tumor necrosis factor receptor superfamily member 9	polymer	163	17523.7	4	UniProt (Q07011) Pfam (PF00020)	Homo sapiens (Human)	4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA
4	M (I)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	N, O, P, Q, R... (A, B, C, D, E...)	water	water		18.0	1196	Chemie (HOH)

Sequence modifications

C, F, I, L: 24 - 180 (UniProt: Q07011)

PDB	External Database	Details
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	167746.8
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	167968.0

*Water molecules are not included.