5ZM7

Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution

Summary for 5ZM7

• Entry DOI: 10.2210/pdb5zm7/pdb
• Descriptor: Oxysterol-binding protein-related protein 1, CHOLESTEROL (2 entities in total)
• Functional Keywords: transporter, complex, lipid, lipid transport
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 50914.97

Authors

Dong, J.,Wang, J.,Wu, J.W. (deposition date: 2018-04-01, release date: 2019-02-27, Last modification date: 2023-11-22)

• Primary citation: Dong, J.,Du, X.,Wang, H.,Wang, J.,Lu, C.,Chen, X.,Zhu, Z.,Luo, Z.,Yu, L.,Brown, A.J.,Yang, H.,Wu, J.W.; Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.; Nat Commun, 10:829-829, 2019; PubMed: 30783101; DOI: 10.1038/s41467-019-08791-0

Experimental method

X-RAY DIFFRACTION (3.401 Å)