5ZEQ

Carboxypeptidase B in complex with DD28

Summary for 5ZEQ

Entry DOI	10.2210/pdb5zeq/pdb
Descriptor	Carboxypeptidase B, ZINC ION, (2~{S})-2-[(6-azanyl-5-chloranyl-pyridin-3-yl)methyl]-3-selanyl-propanoic acid, ... (5 entities in total)
Functional Keywords	selenium, organoselenium, selenol, cpb inhibitor, selectivity, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Sus scrofa (Pig)
Total number of polymer chains	1
Total formula weight	35426.12
Authors	Itoh, T.,Yoshimoto, N.,Yamamoto, K. (deposition date: 2018-02-27, release date: 2018-06-20, Last modification date: 2018-07-04)
Primary citation	Itoh, T.,Yoshimoto, N.,Hirano, Y.,Yamamoto, K. Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group Bioorg. Med. Chem. Lett., 28:2256-2260, 2018 Cited by PubMed: 29859906 DOI: 10.1016/j.bmcl.2018.05.042 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation