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5ZBH

The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885

Summary for 5ZBH
Entry DOI10.2210/pdb5zbh/pdb
DescriptorNeuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1, dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (2 entities in total)
Functional Keywordsg protein-coupled receptor neuropeptide y y1 receptor inhibitor complex structure, signaling protein
Biological sourceHomo sapiens (Human)
More
Cellular locationCell membrane; Multi-pass membrane protein: P25929
Total number of polymer chains1
Total formula weight61255.73
Authors
Yang, Z.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2018-02-11, release date: 2018-04-25, Last modification date: 2018-05-09)
Primary citationYang, Z.,Han, S.,Keller, M.,Kaiser, A.,Bender, B.J.,Bosse, M.,Burkert, K.,Kogler, L.M.,Wifling, D.,Bernhardt, G.,Plank, N.,Littmann, T.,Schmidt, P.,Yi, C.,Li, B.,Ye, S.,Zhang, R.,Xu, B.,Larhammar, D.,Stevens, R.C.,Huster, D.,Meiler, J.,Zhao, Q.,Beck-Sickinger, A.G.,Buschauer, A.,Wu, B.
Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
Nature, 556:520-524, 2018
Cited by
PubMed: 29670288
DOI: 10.1038/s41586-018-0046-x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

数据于2024-03-27公开中

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