5Z9Y

Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP

5Z9Y の概要

• エントリーDOI: 10.2210/pdb5z9y/pdb
• 分子名称: Thiazole synthase, 1-DEOXY-D-XYLULOSE-5-PHOSPHATE (3 entities in total)
• 機能のキーワード: alpha-beta barrel, covalently bound, carbinolamine intermediate, biosynthetic protein, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• 細胞内の位置: Cytoplasm : P9WG73
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52161.53

構造登録者

Zhang, J.,Zhang, B.,Zhao, Y.,Yang, X.,Huang, M.,Cui, P.,Zhang, W.,Li, J.,Zhang, Y. (登録日: 2018-02-05, 公開日: 2018-04-11)

• 主引用文献: Zhang, J.,Zhang, B.,Zhao, Y.,Yang, X.,Huang, M.,Cui, P.,Zhang, W.,Li, J.,Zhang, Y.; Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).; Biochem. Biophys. Res. Commun., 497:214-219, 2018; PubMed: 29428731; DOI: 10.1016/j.bbrc.2018.02.056

実験手法

X-RAY DIFFRACTION (1.48 Å)