5Z8F
Solution structure for the unique dimeric 4:2 complex of a platinum(II)-based tripod bound to a hybrid-1 human telomeric G-quadruplex
Summary for 5Z8F
Entry DOI | 10.2210/pdb5z8f/pdb |
NMR Information | BMRB: 36160 |
Descriptor | G-quadruplex DNA (26-MER), 4-[1-(2,5,8-triazonia-1$l^4-platinabicyclo[3.3.0]octan-1-yl)pyridin-1-ium-4-yl]-N,N-bis[4-[1-(2,5,8-triazonia-1$l^4-platinabicyclo[3.3.0]octan-1-yl)pyridin-1-ium-4-yl]phenyl]aniline (2 entities in total) |
Functional Keywords | g-quadruplex complex, dimeric g-quadruplex, human telomeric g-quadruplex, platinum(ii) complex, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 21957.86 |
Authors | Liu, W.T.,Zhong, Y.F.,Liu, L.Y.,Zeng, W.J.,Wang, F.Y.,Yang, D.Z.,Mao, Z.W. (deposition date: 2018-01-31, release date: 2018-09-19, Last modification date: 2024-05-15) |
Primary citation | Liu, W.,Zhong, Y.F.,Liu, L.Y.,Shen, C.T.,Zeng, W.,Wang, F.,Yang, D.,Mao, Z.W. Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding Nat Commun, 9:3496-3496, 2018 Cited by PubMed: 30158518DOI: 10.1038/s41467-018-05810-4 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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