5Z8A

Crystal structure of GenB1 from Micromonospora echinospora in complex with JI-20A and PLP (external aldimine)

Summary for 5Z8A

Entry DOI	10.2210/pdb5z8a/pdb
Descriptor	C-6' aminotransferase, PYRIDOXAL-5'-PHOSPHATE, (2~{R},3~{R},4~{R},5~{R})-2-[(1~{S},2~{S},3~{R},4~{S},6~{R})-3-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(aminomethyl)-3-azany l-4,5-bis(oxidanyl)oxan-2-yl]oxy-4,6-bis(azanyl)-2-oxidanyl-cyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol, ... (4 entities in total)
Functional Keywords	aminotransferase, plp-binding, transferase
Biological source	Micromonospora echinospora (Micromonospora purpurea)
Total number of polymer chains	2
Total formula weight	95806.18
Authors	Hong, S.K.,Cha, S.S. (deposition date: 2018-01-31, release date: 2019-01-16, Last modification date: 2024-03-27)
Primary citation	Ban, Y.H.,Song, M.C.,Hwang, J.Y.,Shin, H.L.,Kim, H.J.,Hong, S.K.,Lee, N.J.,Park, J.W.,Cha, S.S.,Liu, H.W.,Yoon, Y.J. Complete reconstitution of the diverse pathways of gentamicin B biosynthesis. Nat. Chem. Biol., 15:295-303, 2019 Cited by PubMed: 30643280 DOI: 10.1038/s41589-018-0203-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.398 Å)

Structure validation