5Z7J

Crystal structure of a lactonase double mutant in complex with ligand l

Summary for 5Z7J

• Entry DOI: 10.2210/pdb5z7j/pdb
• Descriptor: Lactonase for protein, (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: alpha/beta-hydrolase, lactonase, zearalenone, hydrolase
• Biological source: Rhinocladiella mackenziei CBS 650.93
• Total number of polymer chains: 8
• Total formula weight: 236014.11

Authors

Zheng, Y.Y.,Liu, W.D.,Chen, C.C.,Guo, R.T. (deposition date: 2018-01-29, release date: 2018-05-02, Last modification date: 2023-11-22)

• Primary citation: Zheng, Y.Y.,Liu, W.T.,Chen, C.C.,Hu, X.Y.,Liu, W.D.,Ko, T.P.,Tang, X.K.,Wei, H.L.,Huang, J.W.,Guo, R.T.; Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity; Acs Catalysis, 8:4294-4298, 2018; DOI: 10.1021/acscatal.8b00464

Experimental method

X-RAY DIFFRACTION (1.98 Å)