5Z6M

High-pressure Crystal Structure Analysis of M20 loop closed DHFR at 800 MPa

Summary for 5Z6M

Entry DOI	10.2210/pdb5z6m/pdb
Descriptor	Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywords	m20 loop closed form, oxidoreductase
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	19562.54
Authors	Watanabe, N.,Nagae, T.,Yamada, H. (deposition date: 2018-01-23, release date: 2018-09-19)
Primary citation	Nagae, T.,Yamada, H.,Watanabe, N. High-pressure protein crystal structure analysis of Escherichia coli dihydrofolate reductase complexed with folate and NADP. Acta Crystallogr D Struct Biol, 74:895-905, 2018 Cited by PubMed: 30198899 DOI: 10.1107/S2059798318009397 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.202 Å)

Structure validation