5Z6F
High-pressure Crystal Structure Analysis of DHFR(0.1 MPa)
Summary for 5Z6F
Entry DOI | 10.2210/pdb5z6f/pdb |
Descriptor | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | m20 loop closed form, oxidoreductase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 19562.54 |
Authors | Watanabe, N.,Nagae, T.,Yamada, H. (deposition date: 2018-01-22, release date: 2018-09-19, Last modification date: 2023-11-22) |
Primary citation | Nagae, T.,Yamada, H.,Watanabe, N. High-pressure protein crystal structure analysis of Escherichia coli dihydrofolate reductase complexed with folate and NADP. Acta Crystallogr D Struct Biol, 74:895-905, 2018 Cited by PubMed: 30198899DOI: 10.1107/S2059798318009397 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.801 Å) |
Structure validation
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