5Z58

Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.

Summary for 5Z58

• Entry DOI: 10.2210/pdb5z58/pdb
• Related: 5Z56 5Z57
• EMDB information: 6889 6890 6891
• Descriptor: Pre-mRNA-processing-splicing factor 8, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, ... (43 entities in total)
• Functional Keywords: spliceosome, cryo-em structure, activated spliceosome, early bact complex, pre-mrna splicing, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 46
• Total formula weight: 2602010.46

Authors

Zhang, X.,Yan, C.,Zhan, X.,Li, L.,Lei, J.,Shi, Y. (deposition date: 2018-01-17, release date: 2018-09-19, Last modification date: 2020-10-14)

• Primary citation: Zhang, X.,Yan, C.,Zhan, X.,Li, L.,Lei, J.,Shi, Y.; Structure of the human activated spliceosome in three conformational states.; Cell Res., 28:307-322, 2018; PubMed: 29360106; DOI: 10.1038/cr.2018.14

Experimental method

ELECTRON MICROSCOPY (4.9 Å)