5Z30

The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant

5Z30 の概要

• エントリーDOI: 10.2210/pdb5z30/pdb
• 分子名称: Histone H3.1, Histone H4, Histone H2A.Z, ... (8 entities in total)
• 機能のキーワード: dna binding, nucleus, chromatin formation, histone fold, histone, nucleosome, chromatin, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 201630.31

構造登録者

Horikoshi, N.,Arimura, Y.,Kurumizaka, H. (登録日: 2018-01-05, 公開日: 2018-07-18, 最終更新日: 2023-11-22)

• 主引用文献: Arimura, Y.,Ikura, M.,Fujita, R.,Noda, M.,Kobayashi, W.,Horikoshi, N.,Sun, J.,Shi, L.,Kusakabe, M.,Harata, M.,Ohkawa, Y.,Tashiro, S.,Kimura, H.,Ikura, T.,Kurumizaka, H.; Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.; Nucleic Acids Res., 46:10007-10018, 2018; PubMed: 30053102; DOI: 10.1093/nar/gky661

実験手法

X-RAY DIFFRACTION (2.45 Å)