5Z14

Crystal structure of human TLR8 in complex with CU-CPT9a

5Z14 の概要

• エントリーDOI: 10.2210/pdb5z14/pdb
• 関連するPDBエントリー: 5WYX 5WYZ
• 分子名称: Toll-like receptor 8, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 190708.50

構造登録者

Tanji, H.,Ohto, U.,Shimizu, T. (登録日: 2017-12-25, 公開日: 2018-07-04, 最終更新日: 2020-07-29)

• 主引用文献: Hu, Z.,Zhang, S.,Tanji, H.,Jiang, S.,Li, J.,Sakaniwa, K.,Jin, J.,Bian, Y.,Ohto, U.,Shimizu, T.,Yin, H.; Inhibition of Toll-like Receptor 8 by Specifically Targeting a Unique Allosteric Site and Locking Its Resting State; To Be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)