5YY9
Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3
Summary for 5YY9
Entry DOI | 10.2210/pdb5yy9/pdb |
Descriptor | E3 ubiquitin-protein ligase UHRF1, Ligase 1 (3 entities in total) |
Functional Keywords | maintenance of dna methylation, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 39604.56 |
Authors | Kori, S.,Defossez, P.A.,Arita, K. (deposition date: 2017-12-08, release date: 2018-12-12, Last modification date: 2023-11-22) |
Primary citation | Kori, S.,Ferry, L.,Matano, S.,Jimenji, T.,Kodera, N.,Tsusaka, T.,Matsumura, R.,Oda, T.,Sato, M.,Dohmae, N.,Ando, T.,Shinkai, Y.,Defossez, P.A.,Arita, K. Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation. Structure, 27:485-, 2019 Cited by PubMed: 30639225DOI: 10.1016/j.str.2018.11.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.653 Å) |
Structure validation
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