5YW7
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)
Summary for 5YW7
Entry DOI | 10.2210/pdb5yw7/pdb |
EMDB information | 6831 6832 6833 6847 |
Descriptor | ATP-binding cassette sub-family C member 8 isoform X2, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total) |
Functional Keywords | katp, channel, glibenclamide, sulfonylurea, membrane protein |
Biological source | Mesocricetus auratus (Golden hamster) |
Total number of polymer chains | 1 |
Total formula weight | 178312.77 |
Authors | |
Primary citation | Wu, J.X.,Ding, D.,Wang, M.,Kang, Y.,Zeng, X.,Chen, L. Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9:553-567, 2018 Cited by PubMed: 29594720DOI: 10.1007/s13238-018-0530-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
Download full validation report