5YW7

Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)

5YW7 の概要

• エントリーDOI: 10.2210/pdb5yw7/pdb
• EMDBエントリー: 6831 6832 6833 6847
• 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
• 機能のキーワード: katp, channel, glibenclamide, sulfonylurea, membrane protein
• 由来する生物種: Mesocricetus auratus (Golden hamster)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 178312.77

構造登録者

Chen, L.,Wu, J.X. (登録日: 2017-11-29, 公開日: 2018-05-02, 最終更新日: 2024-03-27)

• 主引用文献: Wu, J.X.,Ding, D.,Wang, M.,Kang, Y.,Zeng, X.,Chen, L.; Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.; Protein Cell, 9:553-567, 2018; PubMed: 29594720; DOI: 10.1007/s13238-018-0530-y

実験手法

ELECTRON MICROSCOPY (4.4 Å)