5YV9

Structure of CaMKK2 in complex with CKI-009

5YV9 の概要

• エントリーDOI: 10.2210/pdb5yv9/pdb
• 分子名称: Calcium/calmodulin-dependent protein kinase kinase 2, 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: atp-binding, kinase, serine/threonine-protein kinase, transferase, protein-inhibitor complex
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34293.05

構造登録者

Niwa, H.,Handa, N.,Yokoyama, S. (登録日: 2017-11-24, 公開日: 2018-12-05, 最終更新日: 2023-11-22)

• 主引用文献: Takaya, D.,Niwa, H.,Mikuni, J.,Nakamura, K.,Handa, N.,Tanaka, A.,Yokoyama, S.,Honma, T.; Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.; J.Mol.Graph.Model., 99:107599-107599, 2020; PubMed: 32348940; DOI: 10.1016/j.jmgm.2020.107599

実験手法

X-RAY DIFFRACTION (2.53 Å)