5YR6

Human methionine aminopeptidase type 1b (F309L mutant) in complex with TNP470

Summary for 5YR6

Related5YKP 5YR4
DescriptorMethionine aminopeptidase 1, COBALT (II) ION, SODIUM ION, ... (5 entities in total)
Functional Keywordsmetal binding protein, methionine aminopeptidase, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight34689.65
Authors
Pillalamarri, V.,Arya, T.,Addlagatta, A. (deposition date: 2017-11-08, release date: 2018-11-14)
Primary citation
Pillalamarri, V.,Arya, T.,Addlagatta, A.
Discovery of Natural Product Ovalicin Sensitive Type 1 Methionine aminopeptidases: Molecular and Structural Basis
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2163 0.3% 1.5% 9.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5yr6
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Molmil generated image of 5yr6
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Molmil generated image of 5yr6
rotated about y axis by 90°
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