5YQZ

Structure of the glucagon receptor in complex with a glucagon analogue

Summary for 5YQZ

DescriptorGlucagon receptor,Endolysin,Glucagon receptor, Glucagon analogue, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
Functional Keywordshuman gcgr receptor, class b, 7tm domain, membrane, lcp, xfel, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase
Biological sourceHomo sapiens (Human)
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Cellular locationCell membrane ; Multi-pass membrane protein  P47871
Total number of polymer chains2
Total molecular weight72263.78
Authors
Primary citation
Zhang, H.,Qiao, A.,Yang, L.,Van Eps, N.,Frederiksen, K.S.,Yang, D.,Dai, A.,Cai, X.,Zhang, H.,Yi, C.,Cao, C.,He, L.,Yang, H.,Lau, J.,Ernst, O.P.,Hanson, M.A.,Stevens, R.C.,Wang, M.W.,Reedtz-Runge, S.,Jiang, H.,Zhao, Q.,Wu, B.
Structure of the glucagon receptor in complex with a glucagon analogue.
Nature, 553:106-110, 2018
PubMed: 29300013 (PDB entries with the same primary citation)
DOI: 10.1038/nature25153
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.280308.5%3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution