5YQZ

Structure of the glucagon receptor in complex with a glucagon analogue

5YQZ の概要

• エントリーDOI: 10.2210/pdb5yqz/pdb
• 分子名称: Glucagon receptor,Endolysin,Glucagon receptor, Glucagon analogue, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: human gcgr receptor, class b, 7tm domain, membrane, lcp, xfel, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane ; Multi-pass membrane protein : P47871
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72227.75

構造登録者

Zhang, H.,Qiao, A.,Yang, L.,VAN EPS, N.,Frederiksen, K.,Yang, D.,Dai, A.,Cai, X.,Zhang, H.,Yi, C.,Can, C.,He, L.,Yang, H.,Lau, J.,Ernst, O.,Hanson, M.,Stevens, R.,Wang, M.,Seedtz-Runge, S.,Jiang, H.,Zhao, Q.,Wu, B. (登録日: 2017-11-08, 公開日: 2018-01-17, 最終更新日: 2023-11-22)

• 主引用文献: Zhang, H.,Qiao, A.,Yang, L.,Van Eps, N.,Frederiksen, K.S.,Yang, D.,Dai, A.,Cai, X.,Zhang, H.,Yi, C.,Cao, C.,He, L.,Yang, H.,Lau, J.,Ernst, O.P.,Hanson, M.A.,Stevens, R.C.,Wang, M.W.,Reedtz-Runge, S.,Jiang, H.,Zhao, Q.,Wu, B.; Structure of the glucagon receptor in complex with a glucagon analogue.; Nature, 553:106-110, 2018; PubMed: 29300013; DOI: 10.1038/nature25153

実験手法

X-RAY DIFFRACTION (3 Å)