5YPR

Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor

Summary for 5YPR

• Entry DOI: 10.2210/pdb5ypr/pdb
• Related: 5YPO
• Descriptor: Disks large homolog 4, Synthesized GK inhibitor (3 entities in total)
• Functional Keywords: gk maguk inhibitor designed peptide, protein binding
• Biological source: Rattus norvegicus (Rat); More
• Cellular location: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P31016
• Total number of polymer chains: 2
• Total formula weight: 38891.54

Authors

Zhu, J.,Zhou, Q.,Shang, Y.,Weng, Z.,Zhu, R.,Zhang, M. (deposition date: 2017-11-02, release date: 2018-03-14, Last modification date: 2023-11-22)

• Primary citation: Zhu, J.,Zhou, Q.,Shang, Y.,Li, H.,Peng, M.,Ke, X.,Weng, Z.,Zhang, R.,Huang, X.,Li, S.S.C.,Feng, G.,Lu, Y.,Zhang, M.; Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.; Cell Rep, 21:3781-3793, 2017; PubMed: 29281827; DOI: 10.1016/j.celrep.2017.11.107

Experimental method

X-RAY DIFFRACTION (2.349 Å)