5YP4

Crystal structure of dipeptidyl peptidase IV (DPP IV) with Lys-Pro from Pseudoxanthomonas mexicana WO24

Summary for 5YP4

Entry DOI	10.2210/pdb5yp4/pdb
Related	5YP1 5YP2 5YP3
Descriptor	Dipeptidyl aminopeptidase 4, GLYCEROL, LYSINE, ... (5 entities in total)
Functional Keywords	dap iv, clan sc s9, peptidase, dpp4, dpp8, dpp9, hydrolase
Biological source	Pseudoxanthomonas mexicana (Pseudomonas sp. WO24)
Cellular location	Isoform 2: Cytoplasm . Isoform 1: Periplasm : Q6F3I7
Total number of polymer chains	4
Total formula weight	332485.27
Authors	Roppongi, S.,Suzuki, Y.,Tateoka, C.,Fuimoto, M.,Morisawa, S.,Iizuka, I.,Nakamura, A.,Honma, N.,Shida, Y.,Ogasawara, W.,Tanaka, N.,Sakamoto, Y.,Nonaka, T. (deposition date: 2017-11-01, release date: 2018-02-21, Last modification date: 2023-11-22)
Primary citation	Roppongi, S.,Suzuki, Y.,Tateoka, C.,Fujimoto, M.,Morisawa, S.,Iizuka, I.,Nakamura, A.,Honma, N.,Shida, Y.,Ogasawara, W.,Tanaka, N.,Sakamoto, Y.,Nonaka, T. Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues. Sci Rep, 8:2714-2714, 2018 Cited by PubMed: 29426867 DOI: 10.1038/s41598-018-21056-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation