5YNP

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to sinefungin and m7GpppA

Summary for 5YNP

• Entry DOI: 10.2210/pdb5ynp/pdb
• Descriptor: nsp16 protein, nsp10 protein, SINEFUNGIN, ... (6 entities in total)
• Functional Keywords: complex, inhibitor, transferase
• Biological source: Human betacoronavirus 2c EMC/2012; More
• Total number of polymer chains: 2
• Total formula weight: 49940.14

Authors

Wei, S.M.,Yang, L.,Ke, Z.H.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-25, release date: 2018-12-05, Last modification date: 2023-11-22)

• Primary citation: Wei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Yang, Z.Z.,Chen, Y.,Guo, D.Y.,Fan, C.P.; Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.27 Å)