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5YNP

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to sinefungin and m7GpppA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
nsp16 proteinpolymer30333737.61UniProt (K0BWD0)Human betacoronavirus 2c EMC/2012
2B
(B)
nsp10 proteinpolymer14014902.91UniProt (K4LC41)Human betacoronavirus 2c EMC/2012
3C
(A)
SINEFUNGINnon-polymer381.41Chemie (SFG)
PubChem (456189)
PubChem (4065234)
PubChem (6917665)
PubChem (12771337)
PubChem (25246236)
PubChem (176612030)
PubChem (177116271)
PubChem (46875078)
PubChem (46936257)
PubChem (65482)
PubChem (70789212)
PubChem (93287274)
PubChem (12771338)
PubChem (70602121)
PubChem (92403972)
PubChem (93287270)
PubChem (93287272)
PubChem (93475589)
PubChem (131971033)
PubChem (131972810)
PubChem (138626357)
PubChem (156562738)
PubChem (162866891)
PubChem (163339130)
PubChem (168280605)
4D
(A)
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATEnon-polymer787.41Chemie (GTA)
5E, F
(B)
ZINC IONnon-polymer65.42Chemie (ZN)
6G, H
(A, B)
waterwater18.0120Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48640.5
Non-Polymers*Number of molecules4
Total formula weight1299.6
All*Total formula weight49940.1
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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