5YKI
Crystal structure of the engineered nine-repeat PUF domain in complex with cognate 9nt-RNA
Summary for 5YKI
Entry DOI | 10.2210/pdb5yki/pdb |
Related | 5YKH |
Descriptor | Pumilio homolog 1, RNA (5'-R(*UP*GP*UP*UP*GP*UP*AP*UP*A)-3') (3 entities in total) |
Functional Keywords | puf repeats, engineered protein, rna recognition, rna binding protein, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 50896.68 |
Authors | Zhao, Y.Y.,Wang, J.,Li, H.T.,Wang, Z.X.,Wu, J.W. (deposition date: 2017-10-14, release date: 2018-03-14, Last modification date: 2023-11-22) |
Primary citation | Zhao, Y.Y.,Mao, M.W.,Zhang, W.J.,Wang, J.,Li, H.T.,Yang, Y.,Wang, Z.,Wu, J.W. Expanding RNA binding specificity and affinity of engineered PUF domains. Nucleic Acids Res., 46:4771-4782, 2018 Cited by PubMed: 29490074DOI: 10.1093/nar/gky134 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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