5YF4

A kinase complex MST4-MOB4

Summary for 5YF4

Entry DOI	10.2210/pdb5yf4/pdb
Descriptor	MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION, ... (4 entities in total)
Functional Keywords	kinase, complex, phosphorylation, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	21159.67
Authors	Chen, M.,Zhou, Z.C. (deposition date: 2017-09-20, release date: 2018-08-15, Last modification date: 2018-09-26)
Primary citation	Chen, M.,Zhang, H.,Shi, Z.,Li, Y.,Zhang, X.,Gao, Z.,Zhou, L.,Ma, J.,Xu, Q.,Guan, J.,Cheng, Y.,Jiao, S.,Zhou, Z.C. The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer. J. Biol. Chem., 293:14455-14469, 2018 Cited by PubMed: 30072378 DOI: 10.1074/jbc.RA118.003279 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.897 Å)

Structure validation