5YAW

Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction

5YAW の概要

• エントリーDOI: 10.2210/pdb5yaw/pdb
• 分子名称: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, 3-[(4-methoxyphenyl)methylsulfanyl]-5-(2-methylpropyl)-4-(phenylmethyl)-1,2,4-triazole (3 entities in total)
• 機能のキーワード: pde6, oncoprotein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17808.50

構造登録者

Bing, X.,Yanlian, L.,Danyan, C. (登録日: 2017-09-01, 公開日: 2018-09-05, 最終更新日: 2024-03-27)

• 主引用文献: Bing, X.,Yanlian, L.,Danyan, C.; Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction; To Be Published,

実験手法

X-RAY DIFFRACTION (2.027 Å)