5YAV

Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction

Summary for 5YAV

• Entry DOI: 10.2210/pdb5yav/pdb
• Descriptor: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, 1-phenyl-5-propan-2-ylsulfanyl-1,2,3,4-tetrazole (3 entities in total)
• Functional Keywords: pde6delta, oncoprotein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 17661.28

Authors

Bing, X.,Yanlian, L.,Danyan, C. (deposition date: 2017-09-01, release date: 2018-09-05, Last modification date: 2024-03-27)

• Primary citation: Bing, X.,Yanlian, L.,Danyan, C.; Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.989 Å)