5Y8I
Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) + (S)-3-hydroxyisobutyrate (S-HIBA)
Summary for 5Y8I
| Entry DOI | 10.2210/pdb5y8i/pdb |
| Descriptor | Probable 3-hydroxyisobutyrate dehydrogenase, GLYCEROL, (2~{S})-2-methylpentanedioic acid, ... (5 entities in total) |
| Functional Keywords | 3-hydroxy acid dehydrogenase, enzyme substrate interactions, mechanism of enzyme action, oxidoreductase, biosynthetic protein |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Total number of polymer chains | 2 |
| Total formula weight | 60439.00 |
| Authors | Srikalaivani, R.,Singh, A.,Surolia, A.,Vijayan, M. (deposition date: 2017-08-21, release date: 2018-07-11, Last modification date: 2023-11-22) |
| Primary citation | Srikalaivani, R.,Singh, A.,Vijayan, M.,Surolia, A. Structure, interactions and action ofMycobacterium tuberculosis3-hydroxyisobutyric acid dehydrogenase. Biochem. J., 475:2457-2471, 2018 Cited by PubMed: 29959185DOI: 10.1042/BCJ20180271 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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